Publications
Division of Glyco-Signal Research, Institute of Molecular Biomembrane and Glycobiology, Tohoku Pharmaceutical University
Ito, A., Miyazoe, R., Mitoma, J., Akao, T., Osaki, T., and Kunitake, T. Synthetic cationic amphiphiles for liposome-mediated DNA transfection, Biochem. Int. (1990) 22(2), 235
 
Higashi, H., Ito, M., Fukaya, N., Yamagata, S., and Yamagata, T. Two-dimensional mapping by the high-performance liquid chromatography of oligosaccharides released from glycosphingolipids by endoglycoceramidase, Anal. Biochem. (1990) 186(2), 355
 
Higashi, H. N-Glycolylneuraminic Acid-Containing Glycoconjugate as Tumor-Associated Antigen: Hanganutziu-Deicher Antigen, Trends in Glycoscience and Glycotechnology (1990) 2(3), 7
 
Higashi, H. Derivatization of Oligosaccharides from Glycosphingolipids with Aminobenzoic Acid Ethyl Ester and Analysis of Saccharide Structure of Glycosphingolipids by Two-Dimensional Mapping with High Performance Liquid Chromatography, Trends in Glycoscience and Glycotechnology (1990) 2(8), 514
 
Gathuru, J. K., Higashi, H., Kato, S., Usuba, O., and Naiki, M. Use of biotinylated antibody for the assay of Hanganutziu-Deicher antibodies and antigens in fluids and tissues from cancer patients, Jpn. J. Vet. Res. (1989) 37, 71
 
Fukui, Y., Maru, M., Ohkawara, K., Miyake, T., Osada, Y., Wang, D., Ito, T., Higashi, H., Naiki, M., Wakamiya, N., and Kato, S. Detection of glycoproteins as tumor-associated Hanganutziu-Deicher antigen in human gastric cancer cell line, NUGC4, Biochem. Biophys. Res. Commun. (1989) 160(3), 1149
 
Kato, S., and Higashi, H. (1988) N-Glycolylneuraminic acid-containing glycoconjugates, a new tumor associated cell surface antigen known as Hanganutziu-Deicher antigen. Gann Monograph on Cancer Research
 
Higashi, H., Sugii, T., and Kato, S. Specific staining on thin-layer chromatograms of glycosphingolipids of neolacto series and gangliosides with a terminal N-acetylneuraminyl residue by different procedures with wheat germ agglutinin, Biochim. Biophys. Acta (1988) 963, 333
 
Higashi, H., Sasabe, T., Fukui, Y., Maru, M., and Kato, S. Detection of gangliosides as N-glycolylneuraminic acid-specific tumor-associated Hanganutziu-Deicher antigen in human retinoblastoma cells, Japanese Journal of Cancer Research (Gann) (1988) 79(8), 952
 
Yamanaka, T., Hirabayashi, Y., Koketsu, K., Higashi, H., and Matsumoto, M. Highly sensitive analysis of gangliosides in human cerebrospinal fluid with neurological diseases, Jpn. J. Exp. Med. (1987) 57(2), 131
 
Hirabayashi, Y., Kasakura, H., Matsumoto, M., Higashi, H., Kato, S., Kasai, N., and Naiki, M. Specific expression of unusual GM2 ganglioside with Hanganutziu-Deicher antigen activity on human colon cancers, Japanese Journal of Cancer Research (Gann) (1987) 78(3), 251
 
Hirabayashi, Y., Higashi, H., Kato, S., Taniguchi, M., and Matsumoto, M. Occurrence of tumor-associated ganglioside antigens with Hanganutziu-Deicher antigenic activity on human melanomas, Japanese Journal of Cancer Research (Gann) (1987) 78(6), 614
 
Higashi, H., Hirabayashi, Y., Ito, M., Yamagata, T., Matsumoto, M., Ueda, S., and Kato, S. Immunostaining on thin-layer chromatograms of oligosaccharides released from gangliosides by endoglycoceramidase, J. Biochem. (Tokyo). (1987) 102(2), 291
 
Higashi, H., Hirabayashi, Y., Hirota, M., Matsumoto, M., and Kato, S. Detection of ganglioside GM2 in sera and tumor tissues of hepatoma patients, Japanese Journal of Cancer Research (Gann) (1987) 78(12), 1309
 
Miyoshi, I., Higashi, H., Hirabayashi, Y., Kato, S., and Naiki, M. Detection of 4-O-acetyl-N-glycolylneuraminyl lactosylceramide as one of tumor-associated antigens in human colon cancer tissues by specific antibody, Mol. Immunol. (1986) 23(6), 631
 
Hirabayashi, Y., Koketsu, K., Higashi, H., Suzuki, Y., Matsumoto, M., Sugimoto, M., and Ogawa, T. Sensitive enzyme-immunostaining and densitometric determination of ganglio-series gangliosides on thin-layer plate: pmol detection of gangliosides in cerebrospinal fluid, Biochim. Biophys. Acta (1986) 876(1), 178
 
Higashi, H., Hirabayashi, Y., Fukui, Y., Naiki, M., Matsumoto, M., Ueda, S., and Kato, S. Characterization of N-glycolylneuraminic acid-containing gangliosides as tumor-associated Hanganutziu-Deicher antigen in human colon cancer, Cancer Res. (1985) 45(8), 3796
 
Higashi, H., Basu, M., and Basu, S. Biosynthesis in vitro of disialosylneolactotetraosylceramide by a solubilized sialyltransferase from embryonic chicken brain, J. Biol. Chem. (1985) 260(2), 824
 
Higashi, H., Nishi, Y., Fukui, Y., Ikuta, K., Ueda, S., Kato, S., Fujita, M., Nakano, Y., Taguchi, T., Sakai, S., Sako, M., and Naiki, M. Tumor-associated expression of glycosphingolipid Hanganutziu-Deicher antigen in human cancers, Japanese Journal of Cancer Research (Gann) (1984) 75(11), 1025
 
Higashi, H., Ikuta, K., Ueda, S., Kato, S., Hirabayashi, Y., Matsumoto, M., and Naiki, M. Characterization of N-glycolylneuraminic acid-containing glycosphingolipids from a Marek's disease lymphoma-derived chicken cell line, MSB1, as a tumor-associated heterophile Hanganutziu-Deicher antigens, J. Biochem. (Tokyo). (1984) 95(3), 785
 
Higashi, H., Fukui, Y., Ueda, S., Kato, S., Hirabayashi, Y., Matsumoto, M., and Naiki, M. Sensitive enzyme-immunostaining and densitometric determination on thin-layer chromatography of N-glycolylneuraminic acid-containing glycosphingolipids, Hanganutziu-Deicher antigens, J. Biochem. (Tokyo). (1984) 95(5), 1517
 
Ohashi, Y., Sasabe, T., Nishida, T., Nishi, Y., and Higashi, H. Hanganutziu-Deicher heterophile antigen in human retinoblastoma cells, Am. J. Ophthalmol. (1983) 96(3), 321
 
Hirabayashi, Y., Suzuki, T., Suzuki, Y., Taki, T., Matsumoto, M., Higashi, H., and Kato, S. A new method for purification of anti-glycosphingolipid antibody.  Avian anti-hematoside(NeuGc) antibody, J. Biochem. (Tokyo). (1983) 94(1), 327
 
Naiki, M., Fujii, Y., Ikuta, K., Higashi, H., and Kato, S. Expression of Hanganutziu and Deicher type heterophile antigen on the cell surface of Marek's disease lymphoma, Advance in Experimental Medicine and Biology (1982) 152, 445
 
Ikuta, K., Nishi, Y., Shimizu, Y., Higashi, H., Kitamoto, N., Kato, S., Fujita, M., Nakano, Y., Taguchi, T., and Naiki, M. Hanganutziu-Deicher type-heterophile antigen-positive cells in human cancer tissues demonstrated by membrane immunofluorescence, Biken J. (1982) 25(1), 47
 
Higashi, H., and Basu, S. Specific 14C labeling of sialic acid and N-acetylhexosamine residues of glycosphingolipids after hydrazinolysis, Anal. Biochem. (1982) 120(1), 159
 
Fujii, Y., Higashi, H., Ikuta, K., Kato, S., and Naiki, M. Specificities of human heterophilic Hanganutziu and Deicher (H-D) antibodies and avian antisera against H-D antigen-active glycosphingolipids, Mol. Immunol. (1982) 19(1), 87
 
Basu, S., Basu, M., Higashi, H., and Evans, C. H. Biosynthesis and characterization of globoside and Forssman glycosphingolipids in guinea pig tumor cells., Advance in Experimental Medicine and Biology (1982) 152, 131
 
Naiki, M., and Higashi, H. Detection of antibodies to gangliosides in pathogenic human sera.  Serum-sickness type heterophile antibodies, Advance in Experimental Medicine and Biology (1980) 125, 359
 
Higashi, H., Naiki, M., Matuo, S., and Õkouchi, K. Antigen of "serum sickness" type of heterophile antibodies in human sera: Identification as gangliosides with N-glycolylneuraminic acid., Biocemical and Biophysical Research Communications (1977) 79(2), 388
 
 
生体膜情報学研究室
 
分子生体膜研究所 東北薬科大学 English 2001-2009 1991-2000
 -1990
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