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2014

 

1.        Ohta, K.; Ogawa, T.; Kaise, A.; Endo, Y.

Novel Estrogen Receptor (ER) Modulators Containing Various Hydrophobic Bent- Core Structures

Bioorg. Med. Chem. 2014, 22, 3508-3514

 

2013

 

2.        Ohta, K.; Ogawa, T.; Kaise, A.; Endo, Y.

Enhanced Estrogen Receptor beta (ERb) Selectivity of Fluorinated Carborane-containing

ER Modulators

Bioorg. Med. Chem. Lett., 2013, 23, 6555-6558

 

3.        Inomata, K.; Endo, Y.

Synthesis of 2-?Substituted 1,?3-?Cycloheptanedionevia a Lewis Acid Mediated Ring Expansion Reaction

Heterocycles, 2013, 88, 997-1012

 

4.        Ohta, K.; Ogawa, T.; Kaise, A.; Oda, A.; Endo, Y.

Aliphatic Substitution of o-Carboranyl Phenols Enhances Estrogen Receptor Beta Selectivity

Chem. Pharm. Bull., 2013, 62, 386-391

 

5.        Ohta, K.; Kawachi, E.; Shudo, K.; Kagechika, H.

Structure-activity Relationship Study on Benzoic Acid Part of Diphenylamine-based Retinoids

Bioorg. Med. Chem. Lett., 2013, 23, 81-84

 

2012

 

6.        Ohta, K.; Ogawa, T.; Endo, Y.

Estrogenic Activity of B-Fluorinated o-Carborane-1,2-bisphenol Synthesized via SNAr Reaction

Bioorg. Med. Chem., 2012, 20, 4728-4730

 

7.        Fujii, S.; Ohta, K.; Goto, T.; Oda, A.; Masuno, H.; Endo, Y.; Kagechika, H.

Development of Androgen Receptor Ligands by Application of Ten-vertex p-Carborane as a Novel Hydrophobic Core Structure

Med. Chem. Commun., 2012, 3, 680-684

 

8.        Ohta, K.; Taguchi, F.; Endo, Y.

Facile Synthesis and Estrogenic Activity of Arylpyrrole-based Bisphenol Derivatives

Heterocycles, 2012, 86, 165-170

 

2011

 

9.        Fujii, S.; Masuno, H.; Taoda, Y.; Kano, A.; Wongmayura, A.; Nakabayashi, M.; Ito, N.; Shimizu, M.; Kawachi, E.; Hirano, T.; Endo, Y.; Tanatani, A.; Kagechika, H.

Boron Cluster-based Development of Potent Non-Secosteroidal Vitamin D Receptor Ligands: Direct Observation of Hydrophobic Interaction between Protein Surface and Carborane

J. Am. Chem. Soc. 2011, 133, 20933-20941

 

10.    Ohta, K.; Goto, T.; Fujii, S.; Kawahata, M.; Oda, A.; Ohta, S.; Yamaguchi, K.; Hirono, S.; Endo, Y.*

Crystal Structure, Docking Study and Structure?activity Relationship of Carborane-containing Androgen Receptor Antagonist 3-(12-Hydroxymethyl-1,12-dicarba-closo-dodecaboran-1-yl)- benzonitrile.

Bioorg. Med. Chem., 2011, 19, 3540-3548

 

11.    Ohta, K.; Kawachi, E.; Fukasawa, H.; Shudo, K.; Kagechika, H.

Diphenylamine-based Retinoid Anatagonists: Regulation of RAR and RXR Function Depending on the N-substituent

Bioorg. Med. Chem., 2011, 19, 2501-2507

 

12.    Fujii, S.; Yamada, A.; Tomita, K.; Nagano, M.; Goto, T.; Ohta, K.; Harayama, T.; Endo, Y.; Kagechika, H.

p-Carborane Based Androgen Antagonists Active in LNCaP Cells with a Mutated Androgen Receptor

Med. Chem. Commun., 2011, 2, 877-880

 

13.    Wietrzych-Schindler, M.; Szyszka-Niagolov, M.; Ohta, K.; Endo, Y.; Perez, E.; de Lera, A. R.; Chambon, P.; Krezel, W.

Retinoid X Receptor Gamma Is Implicated in Docosahexaenoic Acid Modulation of Despair Behaviors and Working Memory in Mice.

Biol. Psychiatry, 2011, 69, 788-794.

 

14.    Akahane, Y.; Inomata, K.; Endo, Y.

Asymmetric Intramolecular Aldol Reaction Mediated by (S)-N-Substituted -N-(2-pyrrolidinylmethyl)amine to Prepare Wieland-Miescher Ketone.

Heterocycles, 2011, 82: 1727-1737.

 

2010

 

15.        Songkram, C.; Ohta, K.; Yamaguchi, K.; Pichierri, F.; Endo, Y.*

Conformational Control of Benzyl-o-carboranylbenzene Derivatives and Molecular Encapsulation of Acetone into the Dynamically-formed Space of 1,3,5-Tris(2-benzyl-o- carboran-1-yl)benzene.

Inorg. Chem., 2010, 49, 11174?11183.

 

16.        Goto, T.; Ohta, K., Fujii, S.; Ohta, S.;  Endo, Y.*

Design and Synthesis of Androgen Receptor Full Antagonists Bearing a p-Carborane Cage: Promising Ligands for Anti-androgen Withdrawal Syndrome.

J. Med. Chem., 2010, 53, 4917?4926

 

17.        Aizawa, K.; Ohta, K., Endo, Y.*

Synthesis of 3-Aryl-1,2-dicarba-closo-dodecaboranes by Suzuki-Miyaura Coupling Reaction.

Heterocycles, 2010, 80: 369-377.

 

2009

 

18.        Jankowiak, A.; Kaszynski, P.*; Tilford, W. R.; Ohta, K.; Januszko, A.; Nagamine, T.; Endo, Y.

Ring-alkyl Connecting Group Effect on Mesogenic Properties of p-Carborane Derivatives and Their Hydrocarbon Analogues.

Beil, J. Org. Chem., 2009, 5, 1-9.

 

19.        Ohta, K.; Ogawa, T.; Suzuki, T.; Ohta, S.; Endo. Y.*

Novel Estrogen Receptor (ER) Modulators: Carbamate and Thiocarbamate Derivatives with m-Carborane Bisphenol Structure.

Bioorg. Med. Chem., 2009, 17, 7958-7963.

 

20.        Ohta, K.; Yamazaki, H.; Endo, Y.*

Magnesium-Assisted Intramolecular Demethylation Utilizing Carborane C-H Geometry

J. Organomet. Chem., 2009, 694, 1646-1651.

 

21.        Ohta, K.; Konno, S; Endo, Y.*

Complexation of a-Cyclodextrin with Carborane Derivatives in Aqueous Solution

Chem.Pharm. Bull., 2009, 57, 3-7-310.

 

22.        Ogawa, T.; Ohta, K.; Iijima, T.; Suzuki, T.; Ohta, S.; Endo, Y.*

Synthesis and Biological Evaluation of p-Carborane Bisphenols and Their Derivatives: Structure-activity Relationship for Estrogenic Activity

Bioorg. Med. Chem., 2009, 17, 1109-1117.

 

23.        Akahane, Y.; Inomata, K.; Endo, Y.

A new chiral synthesis of Wieland-Miescher ketone catalyzed by a combination of (S)-N-benzyl-(2-pyrrolidinylmethyl)amine derivative and Bronsted acid.

Heterocycles, 2009, 77, 1065-1078.

 

24.    Hirata, M.; Inada, M.; Matsumoto, C.; Takita, M.; Ogawa, T.; Endo, Y.; Miyaura, C.*

A novel carborane Analog, BE360, with a Carbon-containing polyhedral Boron-cluster Is a New Selective Estrogen Receptor Modulator for Bone.

Biochem. Biophys. Res. Commun., 2009, 380, 218-222.

 

2008

 

25.    Kaszynski, P.*; Januszko, A.; Ohta, K.; Nagamine, T.; Potaczek, P.; Young, V. G. Jr.; Endo, Y. Conformational effects on mesophase stability: Numerical comparison of carborane diester homologous series with thier bicyclo[2,2,2]octane, cyclohexane and benzene analogues

Liq. Cryst., 2008, 35, 1169-1190.

 

26.    Fujii, S.; Ohta, K.; Goto, T.; Kagechika, H.; Endo, Y.*

Acidic Heterocycles As Novel Hydrophilic Pharmacophore of Androgen Receptor Ligands with a Carborane Core Structure

Bioorg. Med. Chem., 2009, 17, 344-350.

 

27.    Ohta, K.; Konno, S; Endo, Y.*

Complexation of b-Cyclodextrin with Carborane Derivatives in Aqueous Solution

Tetrahedron Lett. 2008, 49, 6525-6528.

 

28.    Ohta, K.; Chiba, Y.; Ogawa, T.; Endo, Y.*

Promising Core Structure for Nuclear Receptor Ligands: Design and Synthesis of Novel Estrogen Receptor Ligands Based on Diphenylamine Skeleton

Bioorg. Med. Chem. Lett., 2008, 18, 5050-5053.

 

29.    Goto, T.; Fijii, S.; Suzuki, T.; Ohta, S.; Endo, Y.*

Design and Synthesis of Carborane-containing Androgen Receptor (AR) Antagonist Bearing a Pyridine Ring

Bioorg. Med. Chem., 2008, 16, 8022-8028.

 

30.    Nagamine, T.; Inomata, K.*; Endo, Y.

A New Chiral Synthesis of a Bicyclic Endione Containing a Seven-membered Ring Mediated by a Combination of Chiral Amine and Bronsted Acid

Heterocycles, 2008, 76, 1191-1204.

 

31.    Nagamine, T.; Januszko, A.; Ohta, K.; Kaszynski, P.; Endo. Y.

The effect of the linking group on mesogenic properties of three-ring derivatives of p-carborane and biphenyl

Liq. Cryst. 2008, 35, 865?884.

 

32.    Pociecha , D.; Ohta, K.; Januszko, A.; Kaszynski, P.*; Endo, Y.

Symmetric Bent-core Mesogens with m-Carborane and Adamantane As the Central Units

J. Mater. Chem., 2008, 18, 2978 - 2982.

 

33.    Taoda, Y.; Sawabe, T.; Endo, Y.*; Yamaguchi, K.; Fujii, S.; Kagechika, H.*

Identification of an Intermediate in the Deboronation of ortho-Carborane: an Adduct of ortho-Carborane with Two Mucleophiles on One Boron Atom

Chem. Commun., 2008, 2049-2051.

 

34.    Akahane, Y.; Inage, N.; Nagamine, T.; Inomata, K.*; Endo, Y.

An Alternative Chiral Synthesis of Wieland-Miescher Ketone Mediated by (S)-2-(Pyrrolidinylmethyl)pyrrolidine: Remarkable Effects of Bronsted Acid

Heterocycles, 2008, 74, 637-648.

 

2007

 

35.    Ohta, K.; Yamazaki, H.; Pichierri , F.; Kawahata, M.; Yamaguchi, K.; Endo, Y.*

Solid-state Supramolecular Array through Cooperative p-p Interactions of 1-(2-Methoxyphenyl)-o-carborane

Tetrahedron, 2007, 63, 12160-12165.

 

36.    Nagamine, T.; Inomata, K.*; Endo, Y.*

Enantioselective Intramolecular Aldol Reaction Mediated by a Combination of L-Amino Acid and Bronsted Acid to Construct a New Bicyclic Enedione Containing a 7-Membered Ring

Chem.Pharm. Bull., 2007, 55, 1710-1712.

 

37.    Ohta, K.; Yamazaki, H.; Kawahata, M.; Yamaguchi, K.; Pichierri, F.; Endo, Y.*

Proton-Driven Conformational Change in a 2-Aryl-p-carborane Constrained by an Intramolecular C-H---O Hydrogen Bond

Tetrahedron. Lett., 2007, 48, 5231-5234.

 

38.    Ohta, K.; Goto, T.; Yamazaki, H.; Pichierri, F.: Endo, Y.*

Facile and Efficient Synthesis of C-Hydroxycarboranes and C,C'-Dihydroxycarboranes

Inorg. Chem., 2007, 46, 3966-3970

 

39.    Nagamine, T.; Inomata, K.*; Endo, Y.; Paquette, L. A.

Amino Acid-mediated Intramolecular Asymmetric Aldol Reaction to Construct a New Chiral Bicyclic Enedione Containing a 7-Membered Ring: Remarkable Inversion of Enantioselectivity Compared to the 6-Membered Ring.

J. Org. Chem., 2007, 72, 123-131.

 

2006

 

40.    Nagamine, T.; Januszko, A.; Kaszynski, P.*; Ohta, K.; Endo, Y.

Masogenic, Optical and Dielectric Properties of 5-Substituted 2-[12?(4-pentyloxyphenyl)-p- carboran-1-yl][1,3]dioxanes

J. Mater. Chem., 2006, 6, 3836-3843.

 

41.    Calleja, C.; Messaddeq, N.; Chapellier, B.; Yang, H.; Krezel, W.; Li, M.; Metzger, D.; Marcrez, B.; Ohta, K.; kagechika, H,; Endo, Y.; Mark, M.; Ghyselinck, N. B.; Chambon, P.*

Genetic and Pharmacological Evidence that a Retinoic Acid Cannot be the RXR-activating Ligand in Mouse Epidermis Keratinocytes.

Genes Dev., 2006, 20, 1525 - 1538.

 

42.    Ogawa, T.; Ohta, K.; Yoshimi, T.; Yamazaki, H.; Suzuki, T.; Ohta, S.; Endo, Y.*

m-Carborane Bisphenol Structure as a Pharmacophore for Selective Estrogen Receptor Modulators

Bioorg. Med. Chem. Lett., 2006, 16, 3943-3946.

 

43.    Ohta, K.; Yamazaki, H.; Endo, Y.*

NMR Study of 1,2-Dicarba-closo-dodecaboranes: Intramolecular C-H---O Hydrogen Bonding in Solution.

Tetrahedron. Lett., 2006, 47, 1937-1940.

 

2005

 

44.    Ohta, K.; Goto, T.; Endo, Y.*

1,2-Dicarba-closo-dodecaboran-1-yl Naphthalene Derivatives.

Inorg. Chem., 2005, 23, 8569-8573.

 

45.    Nagamine, T.; Januszko, A.; Ohta, K.; Kaszynski, P.; Endo, Y.

A comparison of Mesogenic Properties of p-Carborane-1,12-dicarbaldehyde Schiff Bases with Their Terephthaldehyde Analogues.

Liq. Cryst. 2005, 32, 985-995.

 

46.    Goto, T.; Ohta, K.; Suzuki, T.; Ohta, S.; Endo, Y.*

Design and Synthesis of Novel Androgen Receptor (AR) Antagonists with Sterically Bulky Icosahedral Carboranes.

Bioorg. Med. Chem., 2005, 13, 6414-6424.

 

47.    Fujii, S.; Goto, T.; Ohta, K.; Hashimoto, Y.; Suzuki, T.; Ohta, S.; Endo, Y.*

Potent Androgen Antagonists Based on Carborane As a Hydrophobic Core Structure.

J. Med. Chem. 2005, 48, 4654-4662.

 

48.    Endo, Y*.; Yoshimi, T.; Ohta, K.; Suzuki, T.; Ohta, S.

Potent Estrogen Receptor Ligands Based on Bisphenols with Globular Hydrophobic Cores.

J. Med. Chem. 2005, 48, 3941-3944.

 

49.    Endo, Y.*; Songkram, C.; Ohta, K.; Yamaguchi, K.

Synthesis of Distorted Molecules Based on Spatial Control with Icosahedral Carboranes

J. Organomet. Chem., 2005, 690, 2750-2756.

 

50.    Yamazaki, H.; Ohta, K.; Endo, Y.*

Regioselective Synthesis of Triiodo-o-carboranes and Tetraiodo-o-carborane.

Tetrahedron Lett., 2005, 46, 3119-3122.

 

51.    Endo, Y.*; Songkram, C.; Ohta, K.; Kaszynski, P.; Yamaguchi, K.

A Distorted Benzene Bearing Two Bulky Substituents on Adjacent Positions: Structure of 1,2-Bis(1,2-Dicarba-closo-dodecaboran-1-yl)benzene.

Tetrahedron Lett., 2005, 46, 699-702.

 

52.    Ohta, K.; Goto, T.; Endo, Y.*

New Synthetic Method of 1,2-Diaryl-1,2-dicarba-closo-dodecaboranes Employing Aromatic Nucleophilic Substitution (SNAr) Reaction.

Tetrahedron Lett., 2005, 46, 483-485.

 

53.    Fujii, S.; Hashimoto, Y.; Suzuki, T.; Ohta, S.; Endo, Y*

A new Class of Androgen Receptor Antagonists Bearing Carborane in Place of a Steroidal Skeleton.

BioMed. Chem. Lett. 2005, 15, 227-230.

             

2004

 

54.    Ohta, K.; Iijima, T.; Kawachi, E.; Kagechika, H.; Endo, Y*

Novel Retinoid X Receptor (RXR) Antagonists Having a Dicarba-closo-dodecaborane as a Hydrophobic Moiety.

BioMed. Chem. Lett. 2004, 14, 5913-5918.

 

55.    Endo, Y.*; Ohta, K.; Yoshimi, T.; Yamaguchi, K. A New Application of Inorganic Cluster, Carboranes for Medicinal Drug Design and Molecular Construction.

Phosphorous, Sulfur, and Silicon. 2004, 179, 799-802.

 

56.    Ohta, K.; Januszko, A.; Kaszynski, P.; Nagamine, T.; Sasnouski, G.; Endo, Y.

Structural Effects in Three-Ring Mesogenic Derivatives of p-Carborane and Their Hydrocarbon Analogs.

Liq. Cryst. 2004, 31, 1-12.

 

57.    Suzuki, K.; Inomata, K.; Endo, Y.

Enantiocontrllooed Synthesis of Jasmonates via Tandem Retro-Diels-Alder-Ene reaction Activated by a Silyl Substituent

Org. Lett., 2004, 6, 409-411.

 

2003

 

58.    Taoda, Y.; Endo, Y.*

Electronic Effects of Icosahedral Carboranes: Mechanistic Alteration in Solvolysis of a-(o-Carboranyl)benzyl Tosylates by Electronic Effect of Substituents

Tetrahedron Lett., 2003, 44, 8177-8181.

 

59.    Endo, Y.*; Yamamoto, K.; Kagechika, H.

Utility of Boron Clusters for Drug Design. Relation between Estrogen Receptor Binding Affinity and Hydrophobicity of Phenols Bearing Various Types of Carboranyl Groups.

BioMed. Chem. Lett. 2003, 13, 4089-4092.

 

60.    Johnsamuel, J.; Byun, Y.; Jones, T. P.; Endo, Y.; Tjarks, W.

A Convenient Method for the Computer-Aided Molecular Design of Carborane Containing Compounds.

BioMed. Chem. Lett. 2003, 13,3213-3216.

 

61.    Endo, Y.*; Yoshimi, T.; Miyaura, C.

Boron Clusters for Medicinal Drug Design: Selective Estrogen Receptor Modulators Bearing Carborane

Pure Appl. Chem., 2003, 75, 1197-1205.

 

62.    Johnsamuel, J.; Byun, Y.; Jones, T. P.; Endo, Y.; Tjarks, W.

A New Strategy for Molecular Modeling and Receptor-based Design of Carborane Containing Compounds.

J. Organomet. Chem., 2003, 680, 223-231.

 

63.    Suzuki, K.; Inomata, K.; Endo, Y.

New Chiral Synthesis Methyl and Allyl Disubstituted Butyro Lactone: A Formal Synthesis of (-)-Ngaione

Heterocycles, 2003, 60, 2743-2748.

 

2002

 

64.    Igarashi, Y.; Sekine, A.; Uehara, Y.; Yamaguchi, K.; Endo, Y.; Furumai, T.; Oki, T.

Anicequol, a Novel Inhibitor for Anchorage-independent Growth of Tumor Cells from Penicillium sp. TP-F0213

J. Antibiotics., 2002, 55, 371-376.

 

65.    Toya, T.; Fukasawa, H.; Masui, A.; Endo, Y.*

Potent and Selective Partial Ecdysone Agonist Activity of Chromafenozide in Sf9 Cells

Biochem. Biophys. Res. Commun., 2002, 292, 1087-1091.

 

66.    Endo,Y.*; Songkram, C.; Yamasaki, R.; Tanatani, A.;Kagechika, H.;Takaishi, K.;Yamaguchi, K.

Molecular Construction Based on Icosahedral Carboranes and Aromatic N,Nf-Dimethylurea Groups. Aromatic Layered Molecules and a Transition Metal Complex

J. Organomet. Chem., 2002, 657, 48-58.

 

67.    Toya, T.; Yamaguchi, K.; Endo, Y.*

Cyclic Dibenzoylhydrazines Reproducing the Conformation of Ecdyson Agonists, RH-5849. Importance of Hydrogen-bonding Character of NH Group

BioMed. Chem., 2002, 10, 953-961.

 

 

 

 


”­•\˜_•¶ (1977-2001)

 

 

 

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