2025年
Synthesis and Resolution of 4′-Substituted Nucleosides with Potential Antiviral and Antisense Strategies
Yukino Endo, Kyohei Itoh, Hiroya Kan-no, Hideaki Wakamatsu, Yoshihiro Natori, Yukako Saito, Asako Kaise, Yuhei Nogi, Noriko Saito-Tarashima, Noriaki Minakawa, Yuichi Yoshimura
J. Org. Chem. 2025, 90, 2008-2021.
2024年
濃度依存的に孔径が変化する人工イオンチャネル
皆瀨 麻子
ファルマシア, 2024, 60, 1141.
2023年
An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression
Lisa M. Eubanks, Tossapol Pholcharee, David Oyen, Yoshihiro Natori, Bin Zhou, Ian A. Wilson, Kim D. Janda
ACS Chem. Neurosci., 14, 2023 (2849-2856).
2021年
Synthesis and Properties of 4′-ThioLNA/BNA
Rion Maeda, Noriko Saito-Tarashima, Hideaki Wakamatsu, Yoshihiro Natori, Noriaki Minakawa, Yuichi Yoshimura
Org. Lett., 2021, 23, 4062-4066.
Diastereo- and Enantioselective Intramolecular 1,6-C-H Insertion Reaction of Diaryldiazomethanes Catalyzed by Chiral Dirhodium(II) Carboxylates
Motoki Ito, Yuji Kondo, Ryosuke Namie, Yoshihiro Natori, Koji Takeda, Hisanori Nambu, Masahiro Anada, Yasunori Yamamoto, Shunichi Hashimoto
HETEROCYCLES, 2021, 103, 1078-1098.
A highlyefficaciouscarfentanil vaccine that blunts opioid-induced antinociception and respiratory depression
Eubanks, L.M., Blake, S., Natori, Y., Ellis, B., Bremer, P.T., Janda, K.D.
ACS Chem. Biol., 2021, 16, 277-282.
L-イミノフラノース誘導体の合成とその生物活性評価に関する研究
名取 良浩
YAKUGAKU ZASSHI, 2021, 141, 15-24.
2020年
フェンタニルが混入したヘロインに対するワクチンの合成とその生物活性評価
Synthesis of Drug Vaccine against Heroin Contaminated with Fentanyl and Their Biological Evaluation
名取 良浩, Kim D. Janda
有機合成化学協会誌 ：Journal of Synthetic Organic Chemistry, Japan., 2020, 78, 875-885.
十字路 ELISA（Enzyme-Linked ImmunoSorbent Assay）
名取 良浩
有機合成化学協会誌 ：Journal of Synthetic Organic Chemistry, Japan., 2020, 78, 904.
Strategy for Designing Selective Lysosomal Acid α-Glucosidase Inhibitors: Binding Orientation and Influence on Selectivity
Atsushi Kato, Izumi Nakagome, Mizuki Hata, Robert J. Nash, George W. J. Fleet, Yoshihiro Natori, Yuichi Yoshimura, Isao Adachi, Shuichi Hirono
Molecules, 2020, 25, 2843.
Palladium-Catalyzed Three-Component Coupling of Ynamides
Hideaki Wakamatsu, Ayano Takahashi, Ayaka Ishii, Youhei Kikuchi, Madoka Sasaki, Yukako Saito, Yoshihiro Natori, Yuichi Yoshimura
Organic Letters, 2020, 22, 5299-5303.
Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity
Kanoh, H., Nitta, T., Go, S., Inamori, K., Veillon, L., Nihei, W., Fujii, M., Kabayama, K., Shimoyama, A., Fukase, K., Ohto, U., Shimizu, T., Watanabe, T., Shindo, H., Aoki, S., Sato, K., Nagasaki, M., Yatomi, Y., Komura, N., Ando, H., Ishida, H., Kiso, M., Natori, Y., Yoshimura, Y., Cattaneo, A., Letizia, M., Zonca, A., Ciampa, M., Mauri, M., Prinetti, A., Sonnino, S., Suzuki, A. Inokuchi, J
EMBO J, 2020, 39:e101732.
留学体験記 世界の薬学現場から 第19回 米国留学中の研究について良くない思い出も書いてみた
名取良浩
ファルマシア, 2020, 56, 560-561.
メタレート転位でエノラートが(Z)-ビニルボロン酸エステルに変わる！
Synthesis of 2′-aminouridine derivatives as an organocatalyst for Diels-Alder reaction
Hideaki Wakamatsu, Moeko, Itoh, Yoshihiro Natori, Yoshimura Yuichi
Nucleosides Nucleotides Nucleic Acids, 2020, 39, 365-383.
2019年
A chemically contiguous hapten approach for a heroin-fentanyl vaccine
Yoshihiro Natori, Candy S. Hwang, Lucy Lin, Lauren C. Smith, Bin Zhou, Kim D. Janda
Beilstein J. Org. Chem. 2019, 15, 1020-1031.
Conjugate vaccine produces long-lasting attenuation of fentanyl vs. food choice and blocks expression of opioid withdrawal-induced increases in fentanyl choice in rats
Andrew Townsend, Steven Blake, Kaycee E. Faunce, Candy S. Hwang, Yoshihiro Natori, Bin Zhou, Paul T. Bremer, Kim D. Janda, Matthew L. Bank
Neuropsychopharmacology 2019, 44, 1681-1689.
Catalytic asymmetric synthesis of stereoisomers of 1-C-n-butyl-LABs for the SAR study of α-glucosidase inhibition
Yoshihiro Natori, Toshihiro Sakuma, Haruka Watanabe, Hideaki Wakamatsu, Atsushi Kato, Isao Adachi, Hiroki Takahata, Yuichi Yoshimura
Tetrahedron 2019, 75, 2866-2876.
2018年
Improved Admixture Vaccine of Fentanyl and Heroin Hapten Immunoconjugates: Antinociceptive Evaluation of Fentanyl-Contaminated Heroin
Candy S. Hwang, Lauren C. Smith, Yoshihiro Natori, Beverly Ellis, Bin Zhou, Kim D. Janda
ACS Omega 2018, 3, 11537-11543.
Synthesis of Various Heterocycles Having a Dienamide Moiety by Ring-Closing Metathesis of Ene-ynamides
Hideaki Wakamatsu, Yoshimi Sasaki, Masatoshi Kawahata, Kentaro Yamaguchi, Yuichi Yoshimura
Synthesis 2018, 50, 3467-3486.
Glycosylation reactions mediated by hypervalent iodine: application to the synthesis of nucleosides and carbohydrates
Yuichi Yoshimura, Hideaki Wakamatsu, Yoshihiro Natori, Yukako Saito, Noriaki Minakawa
Beilstein J. Org. Chem. 2018, 14, 1595-1618.
Synthesis of 4'-Thionucleosides as Antitumor and Antiviral Agents.
Yuichi Yoshimura, Yukako Saito, Yoshihiro Natori, Hideaki Wakamatsu
Chem. Pharm. Bull., 2018, 66, 139-146.
Efficient Syntheses of Cocaine Vaccines and Their in Vivo Evaluation.
Atsushi Kimishima, Margaret E. Olson, Yoshihiro Natori, Kim D. Janda
ACS Med. Chem. Lett., 2018, 9, 411-416.
Efficacious Vaccine against Heroin Contaminated with Fentanyl.
Candy S. Hwang, Lauren C. Smith, Yoshihiro Natori, Beverly Ellis, Bin Zhou, Kim D. Janda
ACS Chem. Neurosci., 2018, 9, 1269-1275.
2017年
Development of a Glycosylation Reaction: A Key to Accessing Structurally Unique Nucleosides
Yuichi Yoshimura
Heterocycles 2017, 94, 1625-1651.
Palladium-Catalyzed Regioselective Hydroarylation of Ynamides with Aryl Iodides: Easy Synthesis of Various Substituted Enamides Containing Stilbene Derivatives
Hideaki Wakamatsu, Rika Yanagisawa, Sho Kimura, Nao Osawa, Yoshihiro Natori, Yuichi Yoshimura
Synlett 2017, 28, 2135-2138.
Practical Synthesis of 4′‐Thioribonucleosides from L‐Arabinose via Novel Reductive Ring‐Contraction Reaction and Pummerer‐Type Thioglycosylation
Hideaki Wakamatsu, Kozue Nitta, Nozomi Shoji, Yoshihiro Natori, Yukako Saito, Yuichi Yoshimura
Curr. Protoc. Nucleic Acid Chem., 2017, 71, 1.43.1-1.43.12
2016年
生物活性含窒素複素環化合物の立体選択的合成法の開発：天然物合成並びに有機触媒への応用研究 Development of Stereoselective Synthesis of Biologically active Nitrogen-heterocyclic compounds: Applications for Syntheses of Natural Product and Organocatalyst
名取 良浩，今堀 龍志，吉村 祐一
有機合成化学協会誌 ：Journal of Synthetic Organic Chemistry, Japan., 2016, 74, 335-349.
Docking study and biological evaluation of pyrrolidine-based iminosugars as pharmacological chaperones for Gaucher disease
Atsushi Kato, Izumi Nakagome, Kasumi Sato, Arisa Yamamoto, Isao Adachi, Robert J. Nash, George W. J. Fleet, Yoshihiro Natori, Yasuka Watanabe, Tatsushi Imahori, Yuichi Yoshimura, Hiroki Takahatae, Shuichi Hirono
Org. Biomol. Chem., 2016, 14, 1039-1048.
2015年
Catalytic asymmetric synthesis of (-)-E-δ-viniferin via an intramolecular C?H insertion of diaryldiazomethane using Rh2(S-TFPTTL)4
Yoshihiro Natori, Motoki Ito, Masahiro Anada, Hisanori Nambu, Shunichi Hashimoto
Tetrahedron Letters 2015, 56, 4324-4327.
Construction of an Isonucleoside on a 2,6-Dioxobicyclo[3.2.0]-heptane Skeleton
Yuichi Yoshimura, Satoshi Kobayashi, Hitomi Kaneko, Takeshi Suzuki, Tomozumi Imamichi
Molecules 2015, 20, 4623-4634.
2014年
A Mouse Model of Peripheral Post-Ischemic Dysesthesia: Involvement of Reperfusion-Induced Oxidative Stress and TRPA1 Channel
Sasaki A, Mizoguchi S, Kagaya K, Shiro M, Sakai A, Andoh T, Kino Y, Taniguchi H, Saito Y, Takahata H, Kuraishi Y.
J. Pharmacol. Exp. Ther., 2014, 351, 568-575.
Synthesis and biological evaluation of α-1-C-4′-arylbutyl-L-arabinoiminofuranoses, a new class of α-glucosidase inhibitors
Yoshihiro Natori, Toshihiro Sakuma, Yuichi Yoshimura, Kyoko Kinami, Yuki Hirokami, Kasumi Sato, Isao Adachi, Atsushi Kato, Hiroki Takahata
Bioorg. Med. Chem. Lett., 2014, 24, 3298-3301.
Asymmetric synthesis of 2,5-disubstituted 3-hydroxypyrrolidines based on stereodivergent intramolecular iridium-catalyzed allylic aminations
Yoshihiro Natori, Shunsuke Kikuchi, Takahiro Kondo, Yukako Saito, Yuichi Yoshimura, Hiroki Takahata
Org. Biomol. Chem., 2014, 12, 1983-1994.
Synthesis of a Dihydropyranonucleoside Using an Oxidative Glycosylation Reaction Mediated by Hypervalent Iodine
Hiroya Kan-no, Yukako Saito, Shun Omoto, Sakie Minato, Hideaki Wakamatsu, Yoshihiro Natori, Tomozumi Imamichi, Hiroki Takahata, Yuichi Yoshimura
Synthesis 2014, 46, 879-886.
Gabapentin inhibits bortezomib-induced mechanical allodynia through supraspinal action in mice.
Kitamura R., Andoh T., Miyao S., Saito Y., Takahata H., Kuraishi Y.
J Pharmacol Sci, 2014, 124, 502-510.
2013年
Design and Synthesis of A Nucleoside and A Phosphonate Analogue Constructed on A Branched-threo-tetrofuranose Skeleton
Y. B. Kiran, Hideaki Wakamatsu, Yoshihiro Natori, Hiroki Takahata and Yuichi Yoshimura
Tetrahedron Letters 2013, 54, 3949-3952.
低分子生体成分ミミック体の創出を基盤とする創薬化学研究 Synthetic Medicinal Chemistry of the Biomolecular Components Mimics
高畑 廣紀
YAKUGAKU ZASSHI 2013, 133, 575-585.
A Facile Synthesis of Fully Protected meso-Diaminopimelic Acid (DAP) and Its Application to the Preparation of Lipophilic N-Acyl iE-DAP
Yukako Saito, Yuichi Yoshimura, Hideaki Wakamatsu, Hiroki Takahata
Molecules 2013, 18, 1162-1173.
2012年
α-1-C-Butyl-1,4-dideoxy-1,4-imino-L-arabinitol as a Second-Generation Iminosugar-Based Oral α-Glucosidase Inhibitor for Improving Postprandial Hyperglycemia
Atsushi Kato, Erina Hayashi, Saori Miyauchi, Isao Adachi, Tatsushi Imahori, Yoshihiro Natori, Yuichi Yoshimura, Robert J. Nash, Hideyuki Shimaoka, Izumi Nakagome, Jun Koseki, Shuichi Hirono, Hiroki Takahata
J. Med. Chem. 2012, 55, 10347-10362.
Asymmetric Synthesis of 1-Alkyl-2-deoxyiminofuranoses via The Iridium-catalyzed Intramolecular Cyclization of an Allylic Carbonate
Yoshihiro Natori, Shunsuke Kikuchi, Yuichi Yoshimura, Atsushi Kato, Isao Adachi, Hiroki Takahata
Heterocycles, 2012, 86, 1401-1417.
Recent Advances in Cyclonucleosides: C-Cyclonucleosides and Spore Photoproducts in Damaged DNA
Yuichi Yoshimura, Hiroki Takahata
Molecules, 2012, 17, 11630-11654.
A New Route to N1-Substituted Uracil Derivatives Using Hypervalent Iodine
Yuichi Yoshimura, Hiroya Kan-no, Y. B. Kiran, Yoshihiro Natori, Yukako Saito, Hiroki Takahata
Synthesis 2012, 44, 1163-1170.
Asymmetric Synthesis of 2-Propylisofagomine Using Allylic Hydroxy Group Accelerated Ring-Closing Enyne Metathesis
Taguchi, T.; Imahori, T.; Yoshimura, Y.; Kato, A.; Adachi, I.; Kawahata, M.; Yamaguchi, K.; Takahata, H.
Heterocycles 2012, 84, 929-944.
2011年
An Access to the β-Anomer of 4’-Thio-C-ribonucleosides: Hydroboration of 1-C-Aryl- or 1-C-Heteroaryl-4-thiofuranoid Glycals and Its Regiochemical Outcome
Haraguchi, K.; Horii, C.; Yoshimura, Y.; Ariga, F.; Tadokoro, A.; Tanaka, H.
J. Org. Chem. 2011, 76, 8658-8669.
Docking and SAR studies of D- and L-isofagomine isomers as human β-glucocerebrosidase inhibitors
Kato, A.; Miyauchi, S.; Kato, N.; Nash, R. J.; Yoshimura, Y.; Nakagome, I.; Hirono, S.; Takahata, H.; Adachi, I.
Bioorg. Med. Chem. 2011, 19, 3558-3568.
Synthesis of 5-Thiodidehydropyranylcytosine Derivatives as Potential anti-HIV Agents
Yoshimura, Y.; Yamazaki, Y.; Saito, Y.; Natori, Y.; Imamichi, T.; Takahata, H.
Bioorg. Med. Chem. Lett. 2011, 21, 3313-3316.
ワンポット反応を巧みに利用した(+)-リコフレキシンの全合成
名取良浩
ファルマシア, 2011, 47, 660-661.
The synthesis and biological evaluation of 1-C-alkyl-L-arabinoiminofuranoses, a novel class of α-glucosidase inhibitors
Natori, Y.; Imahori, T.; Murakami, K.; Yoshimura, Y.; Nakagawa, S.; Kato, A.; Adachi, I.; Takahata, H.
Bioorg. Med. Chem. Lett. 2011, 21, 738-741.
Ring-opening metathesis and ring-closing metathesis of bicyclo[4.2.0]octene-ynes: Application to the synthesis of tricyclic compounds
Wakamatsu, H.; Hareyama, S.; Takeshita, M.
Arkivoc 2011, (iv), 104-114.
Catalytic enantioselective C-H functionalization of indoles with α-diazopropionates using chiral dirhodium(II) carboxylates: asymmetric synthesis of the (+)-α-methyl-3-indolylacetic acid fragment of acremoauxin A
Takayuki Goto, Yoshihiro Natori, Koji Takeda, Hisanori Nambu, Shunichi Hashimoto.
Tetrahedron: Asymmetry 2011, 22, 907-915.
2010年
Chemoselective O-tert-butoxycarbonylation of phenols using 6,7-dimethoxyisoquinoline as a novel organocatalyst
Saito, Y.; Yoshimura, Y.; Takahata, H.
Tetrahedron Lett. 2010, 51, 6915-6917.
Synthesis and Antiviral Evaluation of α-D-2’,3’-Didehydro-2’,3’-dideoxy-3’-C-hydroxy- methyl Nucleosides
Yamada, K.; Hayakawa, H.; Sakata, S.; Ashida, N.; Yoshimura, Y.
Bioorg. Med. Chem. Lett., 2010, 20, 6013-6016.
Design and Synthesis of Isonucleosides Constructed on a 2-Oxa-6-thiabicyclo[3.2.0]heptane Scaffold
Yoshimura, Y.; Asami, K.; Imamichi, T.; Kuroda, T.; Shiraki, K.; Takahata, H.
J. Org. Chem.2010, 75, 4161-4171.
Copper-Free Sonogashira Cross-Coupling of Ynamides: Easy Access to Various Substituted Ynamides from Nonsubstituted Ynamides
Wakamatsu, H.; Takeshita, M.
Synlett 2010, 2322-2324.
Ring-closing Metathesis of Ene-ynamide: -Application to the Synthesis of Medium-sized Cyclic Dienamide-
Wakamatsu, H.; Sakagami, M.; Hanata, M.; Takeshita, M.; Mori, M.
Macromol. Symp. 2010, 293, 5-9.
2009年
Synthesis of 1-(5,6-Dihydro-2H-thiopyran-2-yl)uracil by a Pummerer-type Thioglycosylation Reaction: The Regioselectivity of Allylic Substitution
Yoshimura, Y.; Yamazaki, Y.; Saito, Y.; Takahata, H.
Tetrahedron 2009, 65, 9091-9102.
Modified 3-Hydroxypipecolic Acid Derivatives as an Organocatalyst
Yoshimura,Y.; Ohara, C.; Miyagawa, T.; Takahata, H.
Heterocycles 2009, 77, 635-644. (Note)
Asymmetric Synthesis of Neolignans (−)-epi-Conocarpan and (+)-Conocarpan via Rh(II)-Catalyzed C–H Insertion Process and Revision of the Absolute Configuration of (−)-epi-Conocarpan
Natori, Y.; Tsutsui, H.; Sato, N.; Nakamura, S.; Nambu, H.; Shiro, M.; Hashimoto, S.
J. Org. Chem., 2009, 74, 4418-4421.
Catalytic asymmetric Synthesis of both enantiomers of pyrrolizidines 223H’, 239K’, 265H’, and 267H’ found in Msdagascan frogs (Mantella) and their affinities for nicotinic acetylcoline receptor
Saito, Y.; Takahashi, S.; Azerb, N.; Eldefrawi, A. T.; Eldefrawi, M. E.; Takahata , H.
Heterocycles, 2009, 79, 1043-1060.
2008年
Acceleration Effect of Allylic Hydroxy Group on Ring-Closing Enyne Metathesis of Terminal Alkynes: Scope, Application and Mechanistic Insights
Imahori, T.; Ojima, H.; Yoshimura, Y.; Takahata, H.
Chem. Eur. J. 2008, 14, 10762-10771.
A New Entry to Carbocyclic Nucleosides: Oxidative Coupling Reaction of Cycloalkenylsilanes with a Nucleobase Mediated by Hypervalent Iodine Reagent
Yoshimura, Y.; Ohta, M.; Imahori, T.; Imamichi, T.; Takahata, H.
Org. Lett., 2008, 10, 3449-3452.
Synthesis of Both Enantiomers of Hydroxypipecolic Acid Derivatives Equivalent to 5-Azapyranuronic Acids and Evaluation of their Inhibitory Activities against Glycosidases
Yoshimura,Y.; Ohara, C.; Imahori, T.; Saito, Y.; Kato, A.; Miyauchi, S.; Adachi, I.; Takahata, H.
Bioorg. Med. Chem., 2008, 16, 8273-8286.
Synthesis of all stereoisomers of 3-hydroxypipecolic acid and 3-hydroxy-4,5-dehydropipecolic acid and their evaluation as glycosidase inhibitors.
Ohara, C.; Takahashi, R.; Miyagawa, T.; Yoshimura,Y.; Kato, A.; Adachi, I.; Takahata, H.
Bioorg. Med. Chem. Lett., 2008, 18, 1810-1813.
Synthesis of Imidazolium-tagged Ruthenium Carbene Complex: Remarkable Activity and Reusability in Regard to Olefin Metathesis in Ionic Liquids
Wakamatsu, H.; Saito, Y.; Masubuchi, M.; Fujita, R.
Synlett 2008, 1805-1808.
Carboxamidation of carboxylic acids with 1-tert-butoxy-2-tert-butoxycarbonyl-1,2-dihydroisoquinoline (BBDI) without base
Saito, Y.; Ouchi, H.; Takahata, H.
Tetrahedron 2008, 64, 11129-11135.
2007年
A straightforward stereoselective synthesis of meso-(S,S)-and (R,R)-2,6-diaminopimelic acids from cis-1,4-diacetoxycyclohept-2-ene
Saito, Y.; Shinkai, T.; Yoshimura, Y.; Takahata, H.
Bioorg. Med. Chem. Lett., 2007, 17, 5894-5896.
Design and Synthesis of a Novel Ring-expanded 4’-Thio-apio-nucleoside Derivatives
Yoshimura, Y.; Yamazaki, Y.; Kawahata, M.; Yamaguchi, K.; Takahata, H.
Tetrahedron Lett. 2007, 48, 4519-4522.
Asymmetric Synthesis of All Stereoisomers of Isofagomine using [2,3]-Wittig Rearrangement
Mihara, Y.; Ojima, H.; Imahori, T.; Yoshimura, Y.; Ouchi, H.; Takahata, H.
Heterocycles. 2007, 72, 633-645.
A New Preparation of Homochiral N-Protected 5-Hydroxy-3-piperidenes, Promising Chiral Building Blocks, by Palladium-Catalyzed Deracemization of Their Alkyl Carbonates
Takahata, H.; Suto, Y.; Kato, E.; Yoshimura, Y.; Ouchi, H.
Adv. Synth. Catal. 2007, 349, 685-693.
Synthesis of 6,5’-C-Cyclouridine by a Novel Tandem Radical Hydrogen Transfer and Cyclization Reaction
Yoshimura, Y.; Yamazaki, Y.; Wachi, K.; Satoh, S; Takahata, H.
Synlett 2007, 111-114.
Synthesis of Pyrrolizidine, Indolizidine, and Quinolizidine Derivatives Using Ruthenium-Catalyzed Ring-Opening Metathesis and Ring-Closing Metathesis of Cycloalkene-ynes
Wakamatsu, H.; Sato, Y.; Fujita, R.; Mori, M.
Adv. Synth. Catal. 2007, 349(7), 1231-1246.
An asymmetric synthesis of all stereoisomers of piclavines A1-4 using an iterative asymmetric dihydroxylation
Saito, Y.; Okamoto, N.; Takahata, H.
Beils. J. Org. Chem., 2007, 3, 37.
2006年
New Synthesis of (±)-Isonucleosides
Yoshimura, Y.; Asami, K.; Matsui, M.; Tanaka, H.; Takahata, H.
Org. Lett. 2006, 8, 6015-6018.
A Practical Synthesis of 4'-Thioribonucleosides
Yoshimura, Y.; Kuze, T.; Ueno, M.; Komiya, F.: Haraguchi, K.; Tanaka, H.; Kano, F.; Yamada, K.; Asami, K.; Kaneko, N.; Takahata, H.
Tetrahedron Lett. 2006, 47, 591-594.
ROM-RCM of Azabicycloheptene Derivatives - Study of Products Distribution by the Substituent on Alkyne
Mori, M.; Wakamatsu, H.; Sato, Y.; Fujita, R.
J. Mol. Catal. A: Chem. 2006, 254(1-2), 64-67.
Synthesis of Cyclic Dienamide Using Ruthenium-Catalyzed Ring-Closing Metathesis of Ene-ynamide
Mori, M.; Wakamatsu, H.; Saito, N.; Sato, Y.; Narita, R.; Sato, Y.; Fujita, R.
Tetrahedron 2006, 62(16), 3872-3881.
Novel Diels-Alder reaction of 4-nitro-1(2H)-isoquinolones
Fujita, R.; Wakayanagi, S.; Wakamatsu, H.; Matsuzaki, H.
Chem. Pharm. Bull. 2006, 54, 209-212.
Synthesis of 5(6H)-phenanthridones using Diels-Alder reaction of 3-nitro-2(1H)-quinolones acting as dienophiles
Fujita, R.; Yoshisuji, T.; Wakayanagi, S.; Wakamatsu, H.; Matsuzaki, H
Chem. Pharm. Bull. 2006, 54, 204-208.
Ruthenium-Catalyzed ROM-RCM of Cyclopentene-yne. Concise Synthesis of a Pyrrolizidine Derivative
Wakamatsu, H.; Sato, Y.; Fujita, R.; Mori, M.
Heterocycles 2006, 67(1), 89-93.
A Novel tert-butoxycarbonylation reagent: 1-tert-Butoxy-2-tert-butoxycarbonyl-1,2-dihydroisoquinoline (BBDI)
Saito, Y.; Ouchi, H.; Takahata, H.
Tetrahedron, 2006, 62, 11599-11607.
A novel 1-tert-butoxy-2-tert-butoxycarbonyl-1,2-dihydroisoquinoline (BBDI)-catalyzed esterification of N-protected amino acids with nearly equimolar amounts of alcohols in the presence of Boc2O
Saito, Y.; Watanabe, T.; Takahata, H.
Tetrahedron Lett., 2006, 47, 3099-3102.
A new route to trans-2,6-disubstituted piperidine-related alkaloids using a novel C2- symmetric 2,6-diallylpiperidine carboxylic acid methyl ester
Takahata, H.; Saito, Y.; Ichinose, M.
Org. Biomol. Chem., 2006, 4, 1587-1595.
Enantioselective Synthesis of 3-Arylindan-1-ones via Intramolecular C–H Insertion Reactions of α-Diazo-β-ketoesters Catalyzed by Chiral Dirhodium(II) Carboxylates
Natori, Y.; Anada, M.; Nakamura, S.; Nambu, H.; Hashimoto, S.
Heterocycle, 2006, 70, 635-646.
2005年
Synthesis of Isoquinoline Derivatives Using ROM-RCM of Cyclobutene-yne
Mori, M.; Wakamatsu, H.; Tonogaki, K.; Fujita, R.; Kitamura, T.; Sato, Y.
J. Org. Chem. 2005, 70(3), 1066-1069.
Simple and mild esterification of N-Protected amino acids with nearly equimolar amounts of alcohols using 1-tert-butoxy-2-tert-butoxycarbonyl-1,2-dihydroisoquinoline
Saito, Y.; Yamaki, T.; Kohashi, F.; Watanabe, T.; Ouchi, H.; Takahata, H.
Atsushi Kato, Noriko Kato, Erika Kano, Isao Adachi, Kyoko Ikeda, Liang Yu, Tadashi Okamoto, Yasunori Banba, Hidekazu Ouchi, Hiroki Takahata, Naoki Asano
Haraguchi, K.; Shiina, N.; Yoshimura, Y.; Shimada, H.; Hashimoto, K.; Tanaka, H.
Yoshimura, Y.; Kumamoto, H.; Baba, A.; Tanaka, H.
Miura, S.; Yamada, K.; Kano, F.; Yoshimura, Y.
Kitamura, T.; Kuzuba, Y.; Sato, Y.; Wakamatsu, H.; Fujita, R.; Mori, M.
Buschmann, N.; Wakamatsu, H.; Blechert, S.
吉村 祐一
吉村 祐一、高畑 廣紀
吉村 祐一
吉村 祐一
高柳 元明，吉村 祐一，安藤 隆一郎，小島 修樹
吉村 祐一、若松 秀章、名取 良浩、斎藤 有香子
吉村 祐一、高畑 廣紀
吉村 祐一、高畑 廣紀
吉村 祐一、高畑 廣紀
Matsuda, A.; Azuma, A.; Nakajima, Y.; Takenuki, K.; Dan, A.; Iino, T.; Yoshimura, Y.; Minakawa, N.; Tanaka, M.; Sasaki, T.
Tetrahedron Lett., 2005, 46, 1277-1279.
Biological properties of D- and L-1-deoxyazasugars.
J. Med. Chem., 2005, 48, 2036-2044.
2004年
Novel Stereoselective Entry to 2'-β-Carbon-Substituted 2'-Deoxy-4'-thionucleosides from 4-Thiofuranoid Glycals
Org. Lett. 2004, 6, 2645-2648.
Lithiation at the 6-Position of Uridine with Lithium Hexamethyldisilazide: Crucial Role of Temporary Silylation
Org. Lett. 2004, 6, 1793-1795.
Inhibitory Effects of 9-(4-Thio-β-D-ribo-pentofuranosyl)guanine on Tumor Growth and Angiogenesis
Biol. Pharm. Bull. 2004, 27, 520-523.
ROM-RCM of Cycloalkene-yne
Tetrahedron 2004, 60(34), 7375-7389.
An Easily Assembled Highly Active Ruthenium Initiator for Olefin Metathesis
Synlett 2004, 667-670.
総説
Pummerer型チオグリコシル化反応の開発とヌクレオシド合成への応用
東北薬科大学研究誌、第61号、p.1-10 (2014).
グリコシド結合形成反応の開発と新規生物活性ヌクレオシド誘導体合成への展開
有機合成化学協会詩、第67巻、p.798-808 (2009).
コンホメーション固定型アナログである炭素環シクロヌクレオシドの合成と応用研究
東北薬科大学研究誌、第55号、p.9-22 (2008).
解説
免震構造はいかに有効か── 被害が最少限にとどまった東北薬科大学
月刊化学、2011年12月号、p.17-21 (2011).
33年前の震災からの教訓を生かして-免震構造によって守られた大学
日本生理学会雑誌，第74巻，p.151-153 (2012).
著書
中分子創薬に資するペプチド・核酸・糖鎖の合成技術（分担執筆）
CMC出版、2018年、2月
無機化合物・錯体 -生物無機化学の基礎- 第3版（分担執筆）
廣川書店、2016年、4月
無機化合物・錯体 -生物無機化学の基礎- 第2版（分担執筆）
廣川書店、2010年、11月
無機化合物・錯体 -2013生物無機化学の基礎?（分担執筆）
廣川書店、2005年、2月
Design and New Types of Antitumor Nucleosides: The Synthesis and Antitumor Activity of 2'-Deoxy-(2'-C-substituted)cytidines
in Nucleosides Nucleotides as Antitumor and Antiviral Agents; Chu, C. K.; Baker, D. C. Eds.; Plenum Publishing Co., New York, 1993, 1-22.