publication (2016 - )
2018ER subtype selectivity of m-carborane-containing phenols: C-Alkyl groups on the m-carborane cage enhanced ERalpha selectivity.
Kiminori Ohta,* Takumi Ogawa, Koichi Kato, Akifumi Oda, Yasuyuki Endo
Submitted.
Novel androgen receptor full antagonist: Design, synthesis, and a docking study of glycerol and aminoglycerol derivatives that contain p-carborane cages.
Asako Kaise, Kiminori Ohta,* Shinya Fujii, Akifumi Oda, Tokuhito Goto, Yasuyuki Endo
Submitted.
Synthesis, structure-activity relationships, and mechanistic studies of 5-arylazotropolone derivatives as novel xanthine oxidase (XO) inhibiitors.
Daisuke Sato, Takuya Kisen, Mina Kumagai, Kiminori Ohta*
Bioorg. Med. Chem. 2018, 26, 536–542.
2017
Design and synthesis of p-carborane-containing sulfamates as multitarget anti-breast cancer agents.
Asako Kaise, Kiminori Ohta,* Chinami Shirata, Yasuyuki Endo
Bioorg. Med. Chem. 2017, 25, 6417–6426.
Novel p-carborane-containing multitarget anticancer agents inspired by the matabolism of 17beta-estradiol.
Asako Kaise, Kiminori Ohta,* Yasuyuki Endo
Bioorg. Med. Chem. 2017, 25, 6371–6378.
Design and synthesis of iodocarborane-containing ligands with high affinity and selectivity towards ERbeta.
Kiminori Ohta,* Takumi Ogawa, Yasuyuki Endo
Bioorg. Med. Chem. Lett. 2017, 27, 4030–4033.
Structure-activity relations of rosmarinic acid derivatives for the amyloid beta aggregation inhibition and antioxidant properties.
Riho Taguchi, Koki Hatayama, Tomohito Takahashi, Takafumi Hayashi, Yuki Sato, Daisuke Sato, Kiminori Ohta, Hiroto Nakano, Chigusa Seki, Yasuyuki Endo, Kiyotaka Tokuraku, Koji Uwai
Eur. J. Med. Chem. 2017, 138, 1066–1075.
2016
Targeting cancer with PCPA-drug conjugates: LSD1 inhibition-triggered release of 4-hydroxy- tamoxifen.
Ota Yosuke, Yukihiro Itoh, Asako Kaise, Kiminori Ohta, Yasuyuki Endo, Mitsuharu Masuda, Yoshihiro Sowa, Toshiyuki Sakai, Takayoshi Suzuki
Angew. Chem. Int. Ed. 2016, 55, 16115–16118.
Design, synthesis, and anti-proliferative activity of 1-(4-methoxyphenyl)-12-hydroxymethyl-p- carborane derivatives.
Asako Kaise, Kiminori Ohta,* Yasuyuki Endo
Eur. J. Med. Chem. 2016, 122, 257–263.
Symmetric 4,4'-(piperidin-4-ylidenemethylene)bisphenol derivatives as novel tunable estrogen receptor (ER) modulators.
Manabu Sato, Kiminori Ohta,* Asako Kaise, Sayaka Aoto, Yasuyuki Endo
Bioorg. Med. Chem. 2016, 24, 1089–1094.
BE360, a new selective estrogen receptor modulators, produces antidepressant and anti- dementia effects through the enhancement of hippocampal cell proliferation in olfactory bulbectomized mice.
Osamu Nakagawasai, Wataru Nemoto, Hiroshi Onogi, Takahiro Moriya, Jia-Rong Lin, Takayo Odaira, Fukie Yaoita, Takumi Ogawa, Kiminori Ohta, Yasuyuki Endo, Koichi Tan-No
Behav. Brain Res. 2016, 297, 315–322.
